When I started The Sequence years ago, AI was still a relatively niche field, followed closely by researchers, a small group of builders, and a few overly enthusiastic people like me. Today, understanding AI means looking far beyond language models. I increasingly find myself studying frontier areas such as robotics, physical intelligence, scientific discovery, biology, materials, and autonomous laboratories. I would like to share more of that learning with you. Starting soon, we will introduce two new sections'The Sequence Robotics and The Sequence Science'focused on making the most exciting developments in these fields rigorous, accessible, and fun to follow. The most important development this week was Anthropic's release of Opus 5. The model improves long-horizon reasoning, agentic coding, and professional knowledge work while making capabilities previously associated with the most expensive frontier systems more economically usable. The significance is not merely another...
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