By showing individual cells absorbing drugs in real-time, this technology could help scientists test whether new drugs for neurodegenerative disease like Alzheimer's or ALS reach their targets in the brain, with greater speed and resolution. 'The common belief in the field is that if you crank up the power in this type of laser, the light will inevitably become chaotic. But we proved that this is not the case. We followed the evidence, embraced the uncertainty, and found a way to let the light organize itself into a novel solution for bioimaging,' says Sixian You, assistant professor in the MIT Department of Electrical Engineering and Computer Science (EECS), a member of the Research Laboratory for Electronics, and senior author of a paper on this imaging technique. She is joined on the paper by lead author Honghao Cao, an EECS graduate student; EECS graduate students Li-Yu Yu and Kunzan Liu; postdocs Sarah Spitz, Francesca Michela Pramotton, and Federico Presutti; Zhengyu Zhang PhD...
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