Posted by Alumni from Nature
April 28, 2026
The team that made the discovery showed that when the mitochondria ' best known as cells' energy producers ' form these organelles, it helps the parasite to proliferate, although it isn't clear exactly how. Maybe the parasite 'feeds' off the degraded material inside the tiny compartments, says team leader Lena Pernas, an immunologist at the University of California, Los Angeles. But one thing is certain, Pernas said when presenting the findings at a Keystone symposium on mitochondrial signalling, held in Colorado in February: 'Mitochondria are able to give rise to new organelles during infection.' The discovery, posted on 24 April to the preprint server bioRxiv1 ahead of peer review, adds to a growing list of roles that researchers are uncovering for mitochondria in immunity, including surveilling pathogens2 and coordinating immune signalling3. It also lends credence to the hypothesis that membrane sacs, or vesicles, shed by the earliest mitochondria gave rise to organelles in... learn more