Antibody treatments for cancer and other diseases are typically delivered intravenously, because of the large volumes that are needed per dose. This means the patient has to go to a hospital for every treatment, where they may spend hours receiving the infusion. MIT engineers have now taken a major step toward reformulating antibodies so that they can be injected using a standard syringe. The researchers found a way to create solid particles of highly concentrated antibodies, suspended in a solution. These particles carry enough antibodies that only about 2 milliliters of solution would be needed per dose. This advance could make it much easier for patients to receive antibody treatments, and could make treatment more accessible for patients who have difficulty coming into a hospital, including older people. 'As the global population ages, making the treatment process more convenient and accessible for those populations is something that needs to be addressed,' says Talia Zheng, an...
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